Family Portrait
نویسندگان
چکیده
منابع مشابه
A Family Portrait of the RIO
The RIO family of atypical serine protein kinases has been first characterized only recently. It consists of enzymes that contain a unique domain with a characteristic kinase sequence motif and usually some additional domains. At least two RIO proteins, Rio1 and Rio2, are present in organisms varying fromArchaea to humans, with a thirdRio3 subfamily present only in multicellular eukaryotes. Yea...
متن کاملContemporary Family Portrait: The Hidden Uncomfortable Truth of Family Dynamics
This thesis examines the hidden aspect of family dynamic and questions the idealized convention of family portraits. Based on Erving Goffman’s theatrical theory of community, family as a relaxing intimate group in the backstage, the underlying tensions, conflicts, and power play are discussed. This thesis draws upon the familial issues and treatments of Leon J. Saul and Rhee Dong Shick to evalu...
متن کاملA structural portrait of the PDZ domain family.
PDZ (PSD-95/Discs-large/ZO1) domains are interaction modules that typically bind to specific C-terminal sequences of partner proteins and assemble signaling complexes in multicellular organisms. We have analyzed the existing database of PDZ domain structures in the context of a specificity tree based on binding specificities defined by peptide-phage binding selections. We have identified 16 str...
متن کاملPortrait
Born in 1944, I grew up in a world in which polio was both a gripping fear and real threat. Then in a matter of a few years-polio was eradicated by a vaccine developed by Jonas Salk. Later I learned that Salk's efforts were built on pioneering work of many others, including John Enders, Thomas Weller and Frederick Robbins (Nobelists, 1954), and David Bodian, who pioneered studies of polio patho...
متن کاملThe X family portrait: structural insights into biological functions of X family polymerases.
The mammalian family X DNA polymerases (DNA polymerases beta, lambda, mu, and TdT) contribute to base excision repair and double-strand break repair by virtue of their ability to fill short gaps in DNA. Structural information now exists for all four of these enzymes, making this the first mammalian polymerase family whose structural portrait is complete. Here we consider how distinctive structu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2011
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2010.11.044